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Botanical illustration: Harpagophytum (Harpagophytum procumbens DC.)

BOTANICAL ILLUSTRATION · PEDALIACEAE

THE HERBARIUM · PEDALIACEAE

Harpagophytum

Harpagophytum procumbens DC.

This profile concerns tuberous secondary roots. The uses described depend on the preparation.

Part used
Tuberous secondary roots
Origin & distribution
Native range not specified in the medicinal documents considered.

A red, hot, swollen joint or fever: seek medical advice.

BOTANICAL IDENTITY

The right name is the first step.

Also known as: Devil's claw, Devil’s claw

The dossier also covers Harpagophytum zeyheri; comparing extracts requires their exact composition.

An illustration is not enough to identify a plant for consumption. Do not forage for a species based solely on this profile.

01 · UNDERSTAND

Properties & uses.

Traditional use

Minor joint pain

Traditional use; clinical studies are insufficient to establish general effectiveness.

Read the source
Traditional use

Digestion and appetite

Traditional use for bloating and temporary loss of appetite.

Read the source

The traditional uses described are not clinical proof of effectiveness. Evidence for one preparation cannot automatically be applied to another.

02 · UNDERSTAND THE ACTION

How does the plant act?

Devil's claw has mainly been studied for musculoskeletal pain, but products differ: secondary root powder and extracts are not the same intervention. European recognition remains traditional for minor joint pain and certain digestive complaints. Human trials exist; their existence is a reason to describe the preparations and limitations precisely, rather than promise a universal anti-inflammatory effect.

Constituents to know.

Their presence and quantity depend on the plant part and preparation.

Harpagoside
A marker of the WS 1531 extract used in a clinical trial; comparable content is not enough to make two extraction processes equivalent.Read the reference
Traditional use

Minor joint pain

Traditional symptomatic use. Possible pain relief does not prove cartilage protection or that osteoarthritis is halted.

Read the reference
Traditional use

Appetite and digestion

Root preparations also have a traditional use for temporary loss of appetite, flatulence and bloating. These indications do not derive from trials on back pain.

Read the reference

What this means for preparation.

To understand a study, note the extract, solvent and root part, not just “devil's claw.” An identical plant name is not enough to extrapolate results.

03 · EXAMINE THE EVIDENCE

What the research shows.

A laboratory or animal result alone does not demonstrate a benefit in humans. Each result must be read alongside the preparation studied and its limitations.

01Human studies

A trial on flare-ups of low back pain

Type of research
Randomized, double-blind, placebo-controlled trial; 197 patients, four weeks.
Preparation concerned
Oral WS 1531 extract, two controlled exposure levels with harpagoside as a marker.
Observed results
Three patients receiving placebo, six in one extract group and ten in the other were pain-free and required no rescue medication on five days of the final week.
Limitations to consider
This endpoint suggested a favourable signal, but secondary analyses gave a less consistent picture. A short-term result specific to an extract and a flare-up of low back pain.
Read the reference

What can we take from this?

Short trials cannot establish equivalence to an anti-inflammatory medicine, a cure for osteoarthritis or a lasting effect. Digestive and biliary precautions remain relevant.

Documentary review dated 09/10/2026. The references remain available to check the context.

04 · CHOOSE A PREPARATION

One plant, several preparations.

Only forms documented in this profile’s sources are presented.

Herbal tea or powderTuberous secondary roots · Route: oral

Fragmented or powdered root.

Please note: Follow the product's package leaflet; preparations are not interchangeable.

Read the source
ExtractTuberous secondary roots · Route: oral

Documented liquid, soft or dry extracts.

Please note: Follow the product's package leaflet; preparations are not interchangeable.

Read the source

05 · BEFORE ANY USE

Precautions & contraindications.

This guidance does not cover every individual situation. Missing information is not a guarantee of safety.

Contraindications

  • Allergy to the plant.
  • Gastroduodenal ulcer: do not use. Gallstones: seek medical advice beforehand.

Medicine interactions

  • No established interaction is included in this entry; this does not guarantee compatibility with a treatment.

Adverse effects

  • Diarrhea, nausea, abdominal pain, headache, dizziness and allergies have been reported.

Pregnancy & breastfeeding

Pregnancy and breastfeeding: medicinal use is not recommended because of insufficient data.

Children & adolescents

For adults only in this leaflet; insufficient pediatric data.

If symptoms persist, worsen or are unusual, consult a healthcare professional. In an emergency, contact the emergency services.

06 · PUTTING KNOWLEDGE INTO PRACTICE

Preparations & recipes.

No home recipe is provided in this profile. For an appropriate preparation, refer to the product leaflet and ask your pharmacist for advice.

07 · CHECK THE SOURCES

Sources for this profile.

  1. EMA — Harpagophyti radix: assessment and documentsAccessed on 09/10/2026
  2. ANSES — summary of precautions for food supplements (June 2023)Accessed on 09/10/2026
  3. Chrubasik et al., 1999 — WS 1531 extract in flare-ups of low back pain, randomised trialAccessed on 09/10/2026

Illustration: Furukama · CC BY-SA 3.0. View the original image and its licence. Image resized and converted to WebP.

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